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Brought to you by BigRio and Damo.

October 05, 2026 | Issue #345

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The Future of Healthcare Work Is Collaborative

Join Rohit Mahajan and Ritu M. Uberoy, co-hosts of The Big Unlock Podcast, as they discuss how healthcare leaders can build a workforce model that combines human expertise with AI capabilities and smart workflows. 

Explore:

  • How AI agents and voice agents are changing healthcare workflows
  • Where human expertise remains essential, and where AI can provide support
  • High-value opportunities across clinical, administrative, and patient-facing operations
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🔍 Top Insights

  • Google unveils long-awaited Gemini 4 AI model 

 Gemini 4 Argon delivers frontier performance in complex workflows across real-world software engineering, enterprise knowledge work like legal and finance, and cybersecurity defense.

  • SCAN expands reach into Oregon in partnership with the Springs Living  

The products are designed around a care model that seeks to connect the day-to-day support provided to older adults in assisted living communities with their medical care.

The Big Unlock Podcast 

Season 7_Ep228_Social Media1

How the rise of AI-generated health information is changing the way health systems connect consumers to care. 

Learn more

Season 7_Ep227_Social Media1

Don emphasizes that organizations need to look beyond models and focus equally on use cases, ROI, change management, data, and integration. 

Learn more

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Exclusive Offers for The Big Unlock Community

HealthImpact Fall Forum 6-7 Oct SM-01
HIMSS San Diego SM-01
BigUnlockPodcast25 AIMed26

Featured Resource: Generative AI: Unlocking the Next Chapter in Healthcare

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AI Agents won't replace healthcare teams. They'll work alongside them.
The next evolution of Generative AI isn't a single chatbot.


It's intelligent AI agents that can collaborate, retrieve information, automate routine tasks, and support clinicians across complex workflows.
The opportunity isn't simply automation, but enabling clinicians and staff to focus on higher-value work while AI handles repetitive, information-intensive activities.


In Generative AI: Unlocking the Next Chapter in Healthcare, we explore how AI agents fit into the future of healthcare—and why governance and human oversight remain essential as these capabilities evolve.


The future isn't human or AI. It's human expertise amplified by AI.

Get Your Copy

Funding and M&A Moves

  • ARPA-H awards UVM up to $38M for ICU digital twin AI 
  • EliseAI raises $350M at $4B valuation to expand healthcare AI automation 
  • Rightway raises $155M to expand pharmacy benefits technology 

🤖 AI in Action

Use Case of the Week:  AI-Guided Hospital Discharge Planning    

Health System: HonorHealth, Arizona  
  
 

HonorHealth uses predictive AI to establish expected discharge dates, identify potential barriers, and prioritize the actions needed to move patients safely through their care journey. Following implementation across six hospitals, the health system reported a 0.65-day reduction in average length of stay, 50,673 cumulative hospital days saved, and $62 million in savings from reducing excess inpatient days. The percentage of patients receiving an early discharge plan also increased by 72%, reaching 86%. The results show how embedding AI into care-team workflows can improve patient flow, expand bed capacity, and reduce administrative burden. 

    📊 Industry Spotlight

    • Broadband gaps leave rural communities facing multiple barriers to care

    Nearly 12 million people across 41 states live in areas with inadequate broadband, limiting telehealth's potential to reach communities where healthcare is already difficult to access. 

    • Employers increasingly tie digital health payments to outcomes, PHTI survey finds   

    68% of employers and 55% of health plans are tying vendor payments to clinical and financial outcomes, according to PTHI Survey 

    🧠 Thought Leadership

      • Healthcare AI Is Entering Its Accountability Era
      • Health Literacy is the Missing Link to Better Patient Outcomes and Digital Healthcare Transformation 
      • How BigRio Designed a Scalable Patient-Reactivation Model for a Leading U.S. Health System
      • A Leading Research Institute Reinvents Outcomes Research with AI-Assisted Coding

      💬 From the Frontlines

      "Layering technology onto an old process just costs you more, because you still have the old process and you’ve added the technology on top.”

       

      — Roberta L. Schwartz, PhD, EVP and Chief Innovation Officer, Houston Methodist (The Big Unlock Podcast  Episode #224) 

        📅 Upcoming Events

        • HealthImpact Fall Forum 2026 I Oct 6-7, 2026 I New York City  
        • AAO Event I Oct 9-12, 2026 I New Orleans
        • The MedTech Conference 2026 I Oct 18-21 I Boston

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        • C-level Due Diligence Expert/ Advisor 
        • Epic / FHIR Integration Engineer 
        • Senior Vice President – Finance & Investment 
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