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August 11, 2025 l Issue #316

🔍 Top Insights

1. OpenAI CEO Sam Altman says GPT-5 should be used for health
2. White House, Tech Leaders Commit to Create Patient-Centric Healthcare Ecosystem
3. Google would like you to study with Gemini instead of cheat with it

The Big Unlock Podcast

Digital Twins Could Be a Game-Changer for Scalable Healthcare Innovation

With Inderpal Kohli, Healthcare Executive Leader (Englewood Health, HSS, and Columbia University Medical Center)

Learn more

AI If Done Right Can Rehumanize Healthcare

With Ashis Barad, Chief Digital Technology Officer at the Hospital for Special Surgery (HSS)

Learn more

Funding and M&A Moves

• Datavant acquires data retrieval company Ontellus
• Chai Discovery scores $70M for de novo antibody design 

🤖 AI in Action

Use Case of the Week: Scaling AI Co-Workers Across the Enterprise 

Life Sciences Company:  Moderna

Moderna uses over 3,000 GPT-powered agents via ChatGPT Enterprise to enhance R&D, manufacturing, regulatory, and other functions. By combining HR and AI leadership under a Chief People and Digital Technology Officer, it’s scaling AI co-workers to drive productivity and innovation across its 5,000-person workforce. This integration exemplifies how life sciences leaders can scale AI co-workers to boost productivity and innovation enterprise-wide. 

📊 Industry Spotlight

• H1 2025 market overview: big rounds for AI-powered solutions
• Healthcare Industry Trends: 2025 Mid-Year Report

🧠 Thought Leadership

• What Makes a Voice Agent Truly Agentic? 
• Redefining Senior Living – Michael Hughes on Innovation, Social Determinants of Health, and the Future of Aging Care
• Improving Cash Flow Through Smarter Revenue Cycle Management Using AI and Voice Agents (Case Study)
• Unlocking Healthcare’s Future: Ashis Barad’s Vision for Digital Transformation

💬 From the Frontlines

"Agentic AI has the potential to orchestrate entire healthcare workflows—not just moments in time—eliminating friction between silos, improving coordination, and ultimately rehumanizing care by giving clinicians more time with patients."

— Ashis Barad, Chief Digital Technology Officer at the Hospital for Special Surgery (HSS) (Episode 175, The Big Unlock Podcast)

📅 Upcoming Events

• The Current State of Interoperability in Pharmacy and Beyond
  – August 19, 2025 | Online | Webinar
• Designing Voice Agents That Work – Real-World Use Cases, Tools, and Strategies – August 27, 2025 | Online | Zoom

Open Jobs

• Chief Information Officer (CIO)
• AI Digital Twin Engineer – Healthcare Modeling
• AI Engineer – NLP/LLM Data Product Engineer
• Solutions Architect / Senior Engineer – Gen AI Coding
• Bioinformatics ML/AI Engineer
• Principal PySpark Engineer – AWS/EMR

At Cleveland Clinic's AI Summit